Plasticity of sleep in psychiatric disorders

Department of Psychiatry and Psychotherapy

Group Members

Klaus Junghanns (Group Leader)
Nicole Koch (Postdoc)
Maren Schütze (PhD student)
Misha Vithayathil (PhD student)
Stefan Reiche (Medical doctor)
Jolanta Chwalko (Technician)
Andrea Eichler (Technician)


Research Interests

We are investigating the effects of disturbed sleep on sleep and sleep-associated parameters like Memory, Emotion Regulation, HPA-Axis-Functioning, Body Core Temperature and Heart-Rate Variability. In addition we study the reversibility of disturbed sleep and its parameters by the effects of psychotherapy and pharmacotherapy.

The principal disorders being studied are currently Primary Insomnia, Alcohol Dependence, Posttraumatic Stress Disorder (PTSD), and chronic Nightmares. The latter disorder is studied in otherwise healthy subjects, patients with PTSD and patients with a Borderline Personality Disorder.

In addition to these studies on disturbed sleep we investigate several aspects of psychophysioplogical sleep parameters and circadian rhythmicity in healthy subjects like shift workers, different age groups and regular afternoon nappers.

The studies are funded by the Collaborative Research Center SFB/TR-654 Project A9.


Collaborations

  • Robert Göder, Department of Psychiatry and Psychotherapy, University of Kiel
  • Hans-Joachim Frercks, Buchenholm Klinik Bad Malente
  • Jochen Koch, Drägerwerk Lübeck
  • Mareike M. Menz, Neuroimage Nord, Hamburg
  • Tilman Wetterling, Department of Psychiatry, Vivantes Klinikum Hellersdorf, Berlin


Publications

  1. K. Junghanns, M. Schütze, C. Ziems, K. Voigt, B. Böhm, N. Koch, M. Nagel, R. Göder, T. Wetterling (2016): [Influence of alcohol on sleep, cortisol secretion and memory consolidation. Results of a randomised controlled trial.]Somnologie DOI: 10.1007/s11818-015-0035-3
  2. N. Brüggemann, K.-P. Wandinger, C. Gaig, W. Stöcker, K. Junghanns, C. Helmchen, A. Münchau (2016): Dystonia, lower limb stiffness and upward gaze palsy in a patient with IgLON5 antibodies. Movement Disorders (in print)
  3. R. Göder, A. Graf, F. Ballhausen, S. Weinhold, P.C. Baier, K. Junghanns, A. Prehn-Kristensen (2015): Impairment of sleep-related memory consolidation in schizophrenia: relevance of sleep spindles? Sleep Medicine 16(5):564-9
  4. M. Schütze, K. Junghanns (2015): The difficulty of staying awake during alpha/theta neurofeedback training. Appl Psychophysiol Biofeedback. 40(2):85-94.
  5. T. Wetterling, L. Dibbelt, G. Wetterling, R. Göder, F. Wurst , M. Margraf, K. Junghanns (2014): Ethyl glucuronide (EtG): better than breathalyser or self-reports to detect covert short-term relapses into drinking. Alcohol Alcohol. 49(1):51-4.