CBBM Lecture "Dopaminergic modulation of learning and decision-making" by


Marc Guitart Masip, Associate professor, Aging Research Centre, Karolinska Institute


will take place on Tuesday, March 19, 2019 from 15:00 to 16:00 hours in Audimax AM S2.

Host: Prof. Dr. Nico Bunzeck
Institute of Psychology I
University of Lübeck


Abstract

Dopamine has an important role in modulating learning and decision-making and its decline is thought to contribute to impaired decision-making abilities in older adults. In order to better understand the role of dopamine in learning and decision-making, I combine behavioral experiments in younger and older adults along with fMRI measures of regional neuronal activity and PET measures of endogenous dopamine function. I will present data showing the importance of dopaminergic modulation for the emergence of anticipatory value signals using a standard two-armed bandit task tackling probabilistic learning. I will also present data showing that dopaminergic modulation in the dorsal striatum is related to the emergence of a behavioral bias during instrumental learning.


Bioksetch

Marc Guitart-Masip is an associate professor at the Aging Research Center, Karolinska Institute, Sweden where he has established himself as an independent scientist. In parallel he is doing training as a clinical psychiatrist at Psykiatri Nordväst, Stockholm, Sweden. He graduated in medicine in 2002 at Universitat Autònoma de Barcelona and obtained a PhD in Neuroscience at the same university in 2006. During his PhD, he performed experiments in the field of Behavioral and Molecular Pharmacology using animal models of vulnerability to addiction. After obtaining a PhD, his interests expanded to Cognitive Neuroscience and between 2008 and 2012 he was a postdoctoral fellow first at the Institute of Cognitive Neuroscience and thereafter at the Wellcome Trust Centre for Neuroimaging, at University College London (UCL).