Rapid Prototyping of Vascular Anatomy: 3D flow models of brain aneurysms

Institute of Neuroradiology

Group Members

Hannes Schwenke (Group Leader)
Peter Schramm (Principal investigator)
Jakob Seemann (MD Student)

Research Interests

We are a group of highly motivated, tech-savvy scientists and students of medicine and medical engineering who are passionate about interdisciplinary thinking and pioneering ideas in medicine. Using high-resolution neuroimaging, advanced statistical methods, and new segmentation algorithms, we have specialized in high-precision replication of human anatomy, in particular of highly individualized anatomy of human cerebral arteries and their pathological changes.

Through the development of technical-anatomical interfaces using computer-aided design (CAD), we are striving for a complete replication of the human vascular tree. Another focus of our research is the development of new fundamental methods in the field of individual vascular implants, especially for the healing of cerebral artery aneurysms. Therefore, we work with various 3D printing and rapid prototyping techniques and cooperate with various players from science and industry.

In addition, we have many years of experience in training aspiring neurointerventionalists from all over the world to perform endovascular cerebral artery surgery in collaboration with our industrial partners using our 3D-printed vascular phantoms and fully digital intervention simulation.

Collaborations

Latest Publications

  1. Schwenke, H., Calopresti, L., Buzug, T. M., Schramm, P., & Friedrich, T. (2021). Modular simulation of neuroangiography and endovascular interventions in neuroradiology. Transactions on Additive Manufacturing Meets Medicine, 3(1), 578. https://doi.org/10.18416/AMMM.2021.2109578
  2. Bakenecker, A. C., von Gladiss, A., Schwenke, H., Behrends, A., Friedrich, T., Lüdtke-Buzug, K., Neumann, A., Penxová, Z., Barkhausen, J., Wegner, F., & Buzug, T. M. (2021). Fabrication of a steerable magnetic micro-robot. Transactions on Additive Manufacturing Meets Medicine, 3(1), 570.https://doi.org/10.18416/AMMM.2021.2109570
  3. Bakenecker, A.C., von Gladiss, A., Schwenke, H. et al. Navigation of a magnetic micro-robot through a cerebral aneurysm phantom with magnetic particle imaging. Sci Rep 11, 14082 (2021). https://doi.org/10.1038/s41598-021-93323-4
  4. Schwenke, H., Kemmling, A., & Schramm, P. (2019). High-precision, patient-specific 3D models of brain aneurysms for therapy planning and training in interventional neuroradiology. Transactions on Additive Manufacturing Meets Medicine, 1(1). https://doi.org/10.18416/AMMM.2019.1909S03P02